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KMID : 0374919940150020323
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Inje Medical Journal
1994 Volume.15 No. 2 p.323 ~ p.330
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Effects and Safety of a New Oral Inotrophic Agent(Denopamine) in Patients with Chronic Heart Failure
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최석구
김현대/정태기/김대현/김용복/유원상
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Abstract
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Background :
@EN Patients with congestive heart failure have a high mortality rate and are also hospitalized frequently. We studied the effects of a new oral inotrophic agent, denopamine in patients with chronic heart failure.
@ES Methods :
@EN16 patients receiving conventional treatments for heart failure were treated with denopamine 5mg tid for at shortest 3 months. Their history were taken and the physical examination, general laboratory test and the echocardiographic examination
were
done before and after treatment.
@ES Results :
@EN There were 3 deaths and 1 withdrawl because of worsening heart failure. 5 patients (42%) among 12 patients showed the improvement in their subjective symptoms. The fractional shortening and ejection fraction of the left ventricle were
increased
by
3.2% and 5.6% respectively bin their absolute values.
@ES Conclusion :
@EN The addition of denopamine to conventional therapy considerably improved the subjective symptoms and the left ventricular function in the limited number of patients with chronic heart failure.
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KEYWORD
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